JaLCDOI 10.18926/AMO/32181
フルテキストURL fulltext.pdf
著者 Yasumura, Satoshi| Shimizu, Yukihiro| Yasuyama, Toshifumi| Hiroki, Osamu| Okada, Kazuhiko| Tsukishiro, Takashi| Tsuchida, Toshiriro| Higuchi, Kiyohiro| Watanabe, Akiharu|
抄録 <p>Immune responses to hepatitis B virus (HBV) vaccine in six low- or non-responded health-care workers were tested with an intradermal low dose (5 micrograms) of the recombinant vaccine. The injection was repeated three or four times at fortnightly intervals. These successive doses of the vaccine induced a high concentration of antibodies with delayed-type hypersensitivity (DTH) skin reactions in all six subjects. A few minor temporary side effects, such as irritation and itching at the injection site, were reported by some of the vaccinees. The results suggest low-dose of intradermal HBV vaccinations for low- or non-responders are safe and readily effective.</p>
キーワード skin reaction recombinant HBV vaccine
Amo Type Article
発行日 1991-12
出版物タイトル Acta Medica Okayama
45巻
6号
出版者 Okayama University Medical School
開始ページ 457
終了ページ 459
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 1838229
Web of Sience KeyUT A1991GX45300009