JaLCDOI 10.18926/AMO/30878
フルテキストURL fulltext.pdf
著者 Edahiro, Toru| Ohta, Nobuo| Ishii, Akira|
抄録 <p>To analyze the possible major T cell recognition site(s) of chironomid antigens, we established human T cell lines and clones (CD3+ 4+ 8-) reactive to soluble extracts of the adult midge of Tokunagayusurika akamusi (TAA) and/or Chironomus yoshimatsui (CYA). All T cell lines and clones proliferated heavily in response to relatively large molecular weight fractions of TAA (MW greater than or equal to 15,000). Nine clones reactive to TAA were classified into 3 groups according to reactivity, indicating the existence of at least 3 distinct T cell recognition sites in TAA. Five T cell clones responded to both TAA and CYA, although the two chironomid antigens were serologically distinct. We conclude that T cell recognition sites of chironomid antigens are different from B cell recognition sites in humans.</p>
キーワード allergen analysis bronchial asthma chironomid lymphocyte
Amo Type Article
発行日 1989-10
出版物タイトル Acta Medica Okayama
出版者 Okayama University Medical School
開始ページ 261
終了ページ 270
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 2610004
Web of Science KeyUT A1989CA06200002