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ID 57920
フルテキストURL
著者
Yoshimura, Yuuki Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
Kuroda, Masahiro Department of Radiological Technology, Graduate School of Health Sciences, Okayama University Kaken ID researchmap
Sugianto, Irfan Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Khasawneh, Abdullah Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Bamgbose, Babatunde O. Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Hamada, Kentaro Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
Barham, Majd Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Tekiki, Nouha Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kurozumi, Akira Central Division of Radiology, Okayama University Hospital
Matsushita, Toshi Central Division of Radiology, Okayama University Hospital
Ohno, Seiichiro Central Division of Radiology, Okayama University Hospital
Kanazawa, Susumu Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Kaken ID
Asaumi, Junichi Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Kaken ID researchmap
抄録
In order to visualize restricted diffusion, the present study developed a novel method called 'apparent diffusion coefficient (ADC) subtraction method (ASM)' and compared it with diffusion kurtosis imaging (DKI). The diffusion-weighted images of physiological saline, in addtion to bio-phatoms of low cell density and the highest cell density were obtained using two sequences with different effective diffusion times. Then, the calculated ADC values were subtracted. The mean values and standard deviations (SD) of the ADC values of physiological saline, low cell density and the highest cell density phantoms were 2.95 +/- 0.08x10(-3), 1.90 +/- 0.35x10(-3) and 0.79 +/- 0.05x10(-3) mm(2)/sec, respectively. The mean kurtosis values and SD of DKI were 0.04 +/- 0.01, 0.44 +/- 0.13 and 1.27 +/- 0.03, respectively. The ASM and SD values were 0.25 +/- 0.20x10(4), 0.51 +/- 0.41x10(4) and 4.80 +/- 4.51x10(4) (sec/mm(2))(2), respectively. Using bio-phantoms, the present study demonstrated that DKI exhibits restricted diffusion in the extracellular space. Similarly, ASM may reflect the extent of restricted diffusion in the extracellular space.
キーワード
magnetic resonance imaging
apparent diffusion coefficient
diffusion kurtosis imaging
subtraction
restricted diffusion
bio-phantom
cell
発行日
2019-07-25
出版物タイトル
Molecular Medicine Reports
20巻
3号
出版者
Spandidos Publications
開始ページ
2963
終了ページ
2969
ISSN
1791-2997
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
論文のバージョン
publisher
PubMed ID
DOI
Web of Science KeyUT
関連URL
isVersionOf https://doi.org/10.3892/mmr.2019.10523