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タイトル(別表記)
A case of primary aldosteronism with severe hypokalemic myopathy
著者
大谷 裕子 岡山大学医学部第二病理学教室
吉野 正 岡山大学医学部第二病理学教室
赤木 忠厚 岡山大学医学部第二病理学教室
北川 堯之 北川病院
抄録
We report a rare case of primary aldosteronism with severe hypokalemic myopathy in a 59-year-old female who had suffered from hypertension since 1979. Because of severe muscle weakness, especially of extremities, she became unable to rise from her bed and was admitted to the Kitagawa hospital on July 10, 1989. Symptoms such as tetany, polyuria, and diarrhea were not observed. Her consciousness was clear. The blood pressure was in the range of 152 mmHg systolic and 104 mmHg diastolic. Systolic heart murmur (Levine II), cardiac arrythmia, and slight edema on the legs were noticed. She did not have any sign of muscular atrophy. Serum aldosteron level was 220 pg/ml, and plasma renin concentration was less than 0.5 ng/ml/h. The serum level of potassium was 1.7 mEq/l, sodium 150 mEq/l, GOT 47 IU/l, LDH 507 IU/l, CPK 850 IU/l (MM type 99%), and aldolase 9.2 mIU/ml. Computed tomography (CT) after intravenous contrast injection revealed a round low density mass (1.6 cm in diameter) in her left adrenal gland. CT also revealed the gallbladder adenomyomatosis. Her left adrenal gland and gallbladder were surgically removed on July 26, 1989. After the operation, the blood pressure and laboratory data including serum potassium returned to normal, and she became able to pursue her ordinary life. Endoscopy revealed a gastric polyp which was hyperplastic. Histopathologically the removed adrenal gland showed an adrenocortical adenoma consisted of clear cells and nodular hyperplasia of the glomerular zone.
キーワード
低カリウム血性ミオパチー
原発性アルドステロン症
二次性高血圧症
副腎皮質腺腫
発行日
1990-08
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
102巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
843
終了ページ
849
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/102/7-8/102_7-8_843/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma