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ID 17846
Eprint ID
17846
フルテキストURL
Thumnail 84_277.pdf 666 KB
タイトル(別表記)
Studies on serum complement in liver diseases Report 2. Examination to factors affecting the fluctuation of serum complement activity
著者
須藤 千鶴子 岡山大学医学部第一内科学教室
抄録
Various factors to influence serum complement activity were studied in hepatic disorders. The results were as follows: 1) The definit correlation was observed between serum complement hemolytic activity (CH(50)) and immune adherence activity (CIA(50)). As to the complement components in sera with low level of CH(50), C 1, C 2 and C 4 activity were reduced and C 3 activity remained relatively normal. 2) CH(50) levels in patients with hypersplenism were subnormal and returned to normal range after splenectomy. 3) In 5 cases out of 72 patients with active chronic hepatitis, CH(50) levels in the normal range became suddenly unable to be measured by routine method and recovered normal after several weeks or months showing no change in the clinical features. The sera, at the stadium impossible to measure CH(50) levels, inactivated the complement activity of fresh human serum and guinea pig serum, and showed anticomplementary activity suggesting of Ag- Ab- C complex formation. 4) Most of anticomplementary activities in liver cirrhosis were suspected to be non-specific reaction due to abnormal protein metabolism. 5) There was a tendency of the low CH(50) level in cases of 6MP administration, while no influences on CH(50) level fluctuation in clinical course were found with glucocorticosteroids or azathioprine administration.
発行日
1972-10-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
84巻
9-10号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
277
終了ページ
288
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/84/9-10/84_9-10_277/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
6
Eprints Journal Name
joma