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ID 17405
Eprint ID
17405
フルテキストURL
Thumnail 87_393.pdf 1.49 MB
タイトル(別表記)
Effects of total parenteral nutrition on body weight, nitrogen balance and various organs in the immediate post operative period in rats
著者
曽田 益弘 岡山大学医学部外科学第二教室
抄録
The experiment was undertaken to study the effect of total parenteral nutrition (TPN) on nitrogen balance and organs in the postoperative period, 73 of six-week old rats were devided into four groups as follows. Group Ⅰ Simple laparotomy and oral feeding Group Ⅱ Simple laparotomy and TPN Group Ⅲ Intestinal bypass operation and oral feeding Group Ⅳ Intestinal bypass operation and TPN TPN groups received 338 cal/kg/day and 1,96Ng/kg/day administered continuously throughout 13 days. The body weight increase in group Ⅰ, Ⅱ, Ⅲ, and Ⅳ were 66,6g, 55,6g, 4,6g and 42,5g, respectively. The weight gain was observed in TPN groups during postoperative period. The nitrogen balance study in group Ⅱ and Ⅳ showed that positive nitrogen balance was able to achieve in both group and cumulative nitrogen balance in group Ⅱ and Ⅳ was 1,65g and 1,31g, respectively. This study shows that positive nitrogen balance can be obtained in the immediate postoperative period by means of TPN. Small intestine during TPN showed significantly lesser in weight and shorter in villous height than that of oral feeding. The lack of absorption of nutrients from intestinal mucosa seems to be responsible. Histological studies of TPN group revealed that liver and spleen had fatty infiltration and there was swelling of reticuloendothelial cells which is supposed to be due to infusion of fat emulsion. Swollen cells of tubules in the kidney were observed.
発行日
1975-06-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
87巻
5-6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
393
終了ページ
407
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/87/5-6/87_5-6_393/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma