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ID 19549
Eprint ID
19549
フルテキストURL
Thumnail 68_935.pdf 584 KB
タイトル(別表記)
Experimental studies on glutamic acid in rabbits brain with repeated convulsions Part Ⅰ. On free amino-nitrogen and glutamic acid in rabbits brain with repeated convulsions
著者
友沢 久雄 岡山大学医学部第1(陣内)外科教室
抄録(別表記)
The changes of the amount of free amino-nitrogen and glutamic acid were investigated in the rabbits brain with repeated convulsions caused by hexogen. The free amino-nitrogen was measured by Van-Slyke-Neil gasmetric apparatus, and the glutamic acid was measured by Warburg gasmetric apparatus with glutamic acid decarboxylase. The results were as follows. Normal Rabbits Brain During Repeated Convulsions 20-24 Hours after Repeated Convulsions Free Amino-nitrogen 0.4553 mg/g 0.3006 mg/g 0.3324 mg/g Glutamic acid 1.5501 mg/g 0.9543 mg/g 1.2425 mg/g The free amino-nitrogen as well as the glutamic acid were the most in the normal brain and the least during the repeated convulsion, and they showed a certain increase at 20-24 hours after the repeated convulsions compared with those during the convulsions, but still apart from the normal. Glycolysis was depressed by sodium glutamate in the normal rabbits brain which had enough glutamic acid, but the glycolysis was rather accelerated by sodium glutamate in the rabbits brain which had repeated convulsions and thus scarce glutamic acid, when the sodium glutamate was added to the irrigating fluid of the vessels in the brain and then the glycolysis was measured in each irrigating fluid before and after irrigation. Therefore, it could be concluded that sodium glutamate has the effect of regulation to keep the normal and moderate glycolysis in the brain.
発行日
1956-07-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
68巻
7号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
935
終了ページ
943
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/68/7/68_7_935/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
13
Eprints Journal Name
joma