JaLCDOI 10.18926/AMO/31932
フルテキストURL fulltext.pdf
著者 Takahishi, Isao| Yorimitsu, Seiichi| Hara, Masamichi| Inagaki, Toshihiro| Nakada, Hiroyuki| Sekito, Noriko| Hayashi, Naoki| Nonaka, kenichi| Ohmoto, Eijiro| Uchida, Kouzaburo| Takizawa, Michihiro| Kimura, Ikuro| Sanada, Hiroshi| Adachi, Tomiro| Tsubota, Teruhiko| Kitajima, Koichi|
抄録 <p>Thirteen previously untreated patients aged 70 and above with acute nonlymphocytic leukemia were treated with aclarubicin (ACR) alone. Among 10 cases (3, acute myelocytic leukemia; 4, acute myelomonocytic leukemia; 2, acute monocytic leukemia; and one, acute erythroleukemia) in which an evaluation was possible, 5 cases (3, acute myelomonocytic leukemia; and 2, acute monocytic leukemia) obtained complete remission (CR). The CR rate was 83% in 6 patients with acute myelomonocytic leukemia or acute monocytic leukemia. The median CR duration and survival was 7.5 and 10 + months, respectively. Although side effects of the drug on digestive system such as nausea, vomiting and anorexia were observed in all patients, they were controllable by conventional treatments. The results suggest that ACR is effective for the clinical management of elderly patients with acute nonlymphocytic leukemia, especially those with acute myelomonocytic leukemia or acute monocytic leukemia.</p>
キーワード acute leukemia in elderly patients chemotherapy of acute leukemia aclarubicin
Amo Type Article
発行日 1986-06
出版物タイトル Acta Medica Okayama
40巻
3号
出版者 Okayama University Medical School
開始ページ 175
終了ページ 177
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 3461685
Web of Sience KeyUT A1986C914800006