このエントリーをはてなブックマークに追加
ID 49092
フルテキストURL
著者
Sugiura, Yuko Okayama Univ
Soga, Yoshihiko Okayama Univ
Nishide, Sachiko Okayama Univ Hosp Med & Dent
Kono, Kotoe Okayama Univ Hosp Med & Dent
Takahashi, Kanayo Okayama Univ Hosp Med & Dent
Fujii, Nobuharu Okayama Univ
Ishimaru, Fumihiko Okayama Univ
Tanimoto, Mitsune Okayama Univ
Nishimura, Fusanori Okayama Univ
Takashiba, Shogo Okayama Univ
抄録
Goals Hematopoietic cell transplantation (HCT) may lead to the development of xerostomia. However, there have been few reports of xerostomia in HCT patients based on objective data. We investigated moisture in the oral mucosa in patients undergoing HCT by the capacitance method using a convenient device, Moisture Checker for Mucus (R) (MCM; Life Co., Ltd., Saitama, Japan). Subjects and methods Thirty-six patients undergoing HCT at Okayama University Hospital of Medicine and Dentistry (Male=22, Female=14; age=41.6 +/- 16.2 years old) were enrolled in this study. Moisture in the oral mucosa was measured by MCM in accordance with the manufacturer's instructions. The results were obtained as MCM values (%), which are the weight percentage of water content in the oral mucosal epithelium. As controls, moisture of the oral mucosa was also examined in healthy volunteers (Male=27, Female=35; age=43.0 +/- 14.6 years old). Main results Throughout the examination period, MCM values were significantly lower in patients who underwent HCT than in controls. The degree of mucosal moisture in HCT patients showed wide interindividual differences. Conclusion The degree of mucosal moisture in HCT patients was low and showed wide interindividual differences. Evaluation of xerostomia using such a device may contribute to appropriate oral care with saliva substitute.
キーワード
xerostomia
hematopoietic cell transplantation
hyposalivation
発行日
2008-10
出版物タイトル
Supportive Care in Cancer
16巻
10号
開始ページ
1197
終了ページ
1200
ISSN
0941-4355
資料タイプ
学術雑誌論文
オフィシャル URL
http://dx.doi.org/ 10.1007/s00520-008-0470-9
言語
English
論文のバージョン
author
査読
有り
DOI
PubMed ID
Web of Sience KeyUT