著者 Kondo, Kazuo| Yonezawa, Toshihiro| Mikami, Daisuke| Okubo, Toshikazu| Taguchi, Yuichi| Takahashi, Kenji| Barkey, Dale P|
発行日 2005-09
出版物タイトル Journal of the Electrochemical Society
152巻
11号
資料タイプ 学術雑誌論文
著者 Sun, Jian-Jun| Kondo, Kazuo| Okamura, Takuji| Oh, SeungJin| Tomisaka, Manabu| Yonemura, Hitoshi| Hoshino, Masataka| Takahashi, Kenji|
発行日 2005-09
出版物タイトル Journal of the Electrochemical Society
152巻
11号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/30326
フルテキストURL fulltext.pdf
著者 Tsuji, Takao| Takahashi, Kenji| Naito, Kunihiko| Nagashima, Hideo|
抄録 <p>An enzyme-linked immunosorbent assay (ELISA) for the detection of serum blocking factors (BF), or antibodies to the albumin receptor on HBsAg particles, was developed, and its clinical usefulness was examined in healthy persons and patients with liver diseases. Thirteen of 80 anti-HBs-positive female (16.3%) had BF, but all 25 male anti-HBs-positive, 41 female and 32 male anti-HBs-negative subjects were negative for BF. The activity of BF in BF-positive cases was not associated with the positive reciprocal hemagglutination titer of anti-HBs. For a neutralization test of BF, the BFs from 5 cases were absorbed with IgG-immunobeads. It was determined that these IgG-BFs were antibodies to the albumin receptors on HBsAg particles. No significance between positive-BF and abnormal S-GPT levels was recognized. These results suggest that the present test for the detection of BF, or anti-albumin receptor antibody, different from anti-HBs, might be useful for diagnosis of hepatitis B and as a marker for HB virus.</p>
キーワード HBV blocking factor to albumin receptor antibody to albumin receptor albumin receptor ELISA
Amo Type Brief Note
発行日 1984-04
出版物タイトル Acta Medica Okayama
38巻
2号
出版者 Okayama University Medical School
開始ページ 175
終了ページ 180
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 6731028
Web of Sience KeyUT A1984SN81800009
JaLCDOI 10.18926/AMO/30320
フルテキストURL fulltext.pdf
著者 Shiota, Tetsuya| Watanabe, Akiharu| Itoshima, Tatsuya| yamamoto, Hiroshi| Takahashi, Kenji| Nagashima, Hideo|
抄録 <p>Two cases of chronic unconjugated hyperbilirubinemia and marked retention of indocyanine green (ICG) are described. Since bilirubin uridine diphosphate (UDP)-glucuronyl transferase activities were depressed in their liver, the patients seemed to have bilirubin metabolism similar to that in Gilbert's syndrome. However, the ICG fractional disappearance rates of the cases were rather low (0.018 and 0.019) compared to the rates reported for Gilbert's syndrome. These results suggest that the patients had a new metabolic disorder which results in constitutional unconjugated hyperbilirubinemia and ICG intolerance.</p>
キーワード Gilbert's syndrome indocyanine green bilirubin
Amo Type Brief Note
発行日 1984-12
出版物タイトル Acta Medica Okayama
38巻
6号
出版者 Okayama University Medical School
開始ページ 565
終了ページ 567
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 6441454
Web of Sience KeyUT A1984TX98000009