JaLCDOI 10.18926/AMO/32417
フルテキストURL fulltext.pdf
著者 Makino, Hirofumi| Toyofuku, Hiroyuki| Mino, Yasuaki| Takaoka, Michio| Ota, Zensuke|
抄録 <p>Descemet's membrane was isolated from the corneas of cows and observed by electron microscopy after negative staining with 1% phosphotungstic acid solution, pH 7.2. Ultrastructurally, bovine Descement's membrane had a very regular hexagonal pattern. Nodes were connected to the six others around each of them by thin filaments to form a hexagon. The distance between the nodes was approximately 120 nm, the diameter of the nodes approximately 30 nm, and the width of the connecting filaments approximately 10 nm. Bovine Descement's membrane was a molecular sieve composed of nodes and filaments substantiating our molecular sieve theory of basement membranes.</p>
キーワード basement membrance cornea Descemet's membrance electron microscopy
Amo Type Brief Note
発行日 1983-04
出版物タイトル Acta Medica Okayama
37巻
2号
出版者 Okayama University Medical School
開始ページ 155
終了ページ 157
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 6191527
Web of Sience KeyUT A1983QN63900008
JaLCDOI 10.18926/AMO/31729
フルテキストURL fulltext.pdf
著者 Ichiyasu, Akira| Takaoka, Michio| Makino, Hirofumi| Takahashi, Kayo| Ota, Zensuke|
抄録 <p>Rat kidney glomerular basement membrane (GBM) was isolated and digested with alpha-amylase and elastase. Electron microscopy revealed a meshwork structure composed of fibrils 3 nm in width. They appeared to be type IV collagen fibrils. We succeeded in clarifying a significant ultrastructural aspect of the GBM which had been unclear until now. The findings are consistent with our previously proposed GBM molecular sieve theory.</p>
キーワード type IV collagen glomerular basement membrane enzymatic digestion fibrillar ultrastructure
Amo Type Article
発行日 1987-08
出版物タイトル Acta Medica Okayama
41巻
4号
出版者 Okayama University Medical School
開始ページ 183
終了ページ 185
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 3499055
Web of Sience KeyUT A1987J833200007
JaLCDOI 10.18926/AMO/31499
フルテキストURL fulltext.pdf
著者 Nishiya, Koji| Matsueda, Hideki| Shirakami, Toshiaki| Hatano, Makoto| Yano, Keisuke| Ogura, Toshiro| Takaoka, Michio| Hiraki, Yoshio| Aono, Kaname| Ezawa, Hidemitsu| Ota, Zensuke|
抄録 <p>The serum and urinary ferritin levels in 52 RA patients were measured by the 2-site immunoradiometric assay method. Serum ferritin levels in RA patients correlated with C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) but not with serum iron levels and hemoglobin concentrations, although they were within the normal range. High serum ferritin levels were associated with sera with hyper gamma-globulin and rheumatoid factors. In sequential studies, serum ferritin changed in parallel with ESR, CRP and disease activity in a majority of the patients. The urinary ferritin levels and u/s ratios in some RA patients were higher than control values. Higher values were found particularly in the group of patients under gold therapy but not in groups under other treatments.</p>
キーワード rheumatoid arthritis serum ferritin urinary ferritin gold therapy
Amo Type Article
発行日 1985-08
出版物タイトル Acta Medica Okayama
39巻
4号
出版者 Okayama University Medical School
開始ページ 321
終了ページ 328
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 2413723
Web of Sience KeyUT A1985APN0700008
JaLCDOI 10.18926/AMO/31274
フルテキストURL fulltext.pdf
著者 Makino, Hirofumi| Takaoka, Michio| Komoda, Keizo| Tokuyama, Kiyoyuki| Ota, Zensuke| Ofuji, Tadashi| Kaneshige, Tetsuji|
抄録 <p>Masugi nephritis was induced in rats by a single intravenous injection of rabbit anti-rat kidney serum, and studied with a scanning electron microscope. A characteristic finding was the presence of white cells, probably polymorphonuclear leukocytes, with many microspikes which penetrated through degenerated glomerular endothelial cells to be in direct contact with the glomerular basement membrane. This finding confirms the pathogenic role of leukocytes in glomerulonephritis induced by anti-glomerular basement membrane antibody.</p>
キーワード Masugi nephritis scanning electron microscopy leukocyte.
Amo Type Brief Note
発行日 1981-11
出版物タイトル Acta Medica Okayama
35巻
5号
出版者 Okayama University Medical School
開始ページ 373
終了ページ 376
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 6459000
Web of Sience KeyUT A1981MS42400007