このエントリーをはてなブックマークに追加
ID 32638
JaLCDOI
フルテキストURL
著者
Kuroda, Masahiro Okayama University
Inamura, Keiji Okayama University
Tahara, Seiji Okayama University
Mimura, Seiichi Okayama University
Mikami, Yasutaka Okayama University
Kawasaki, Shoji Okayama University
Hiraki, Yoshio Okayama University
抄録

Simultaneous radiohyperthermotherapy (SRH) is a combined hyperthermia-radiation therapy in which irradiation is given during heating. Mutual interference between the high energy radiotherapy system (Toshiba LMR-15A) and the 13.56 MHz capacitive heating system (Omron HEH-500C) was tested with phantom materials prior to a clinical trial with SRH. The energy and flatness of irradiation were not affected by the heating system within the range of clinical use. The high energy radiotherapy system did not affect the increase or distribution of temperature during simultaneous treatment. The results of this phantom study indicated that these apparatuses would not produce clinically significant mutual interference during SRH. A clinical trial was performed on a 57-year-old woman with postoperative recurrence of rectal cancer. This is the first reported clinical case treated with true SRH in which external irradiation was administered during mid capacitive heating. Twelve SRH treatments were performed on the recurrent lesion at a frequency of twice a week for six weeks using the apparatuses described above. There was a significant reduction in pain after treatment. The tumor marker carcinoembryonic antigen (CEA) level decreased after treatment. On CT images taken after treatment, the tumor site became a low density area which indicated necrosis. There were no side effects. These results suggest that further clinical study of SRH should be performed to clarify its advantages.

キーワード
hyperthermia
capacitive heating
radiotherapy
phantom study
simultaneous radio-hyperthermotherapy
Amo Type
Article
発行日
1992-12
出版物タイトル
Acta Medica Okayama
46巻
6号
出版者
Okayama University Medical School
開始ページ
417
終了ページ
426
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT