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ID 16350
Eprint ID
16350
フルテキストURL
Thumnail 95_721.pdf 2.89 MB
タイトル(別表記)
Studies on cell-mediated immunity in patients with malignant tumor. Part II. Leukocyte migration inhibition test in patients with malignant lymphoma.
著者
寺尾 誠也 岡山大学医学部第2内科学教室
抄録
Three different procedures of the leukocyte migration inhibition test(LMIT) were performed in order to study cell-mediated immunity in patients with malignant lymphoma. Using sonicated antigens from normal lymphocytes and lymphoma cells obtained by lymphnode biopsy, leukocytes from patients with malignant lymphoma showed a positive reaction exclusively against antigens obtained from malignant lymphoma cells. It was suggested that patients with malignant lymphoma had a cell-mediated immunity against the tumor-associated antigens. The migration index of LMIT using autochthonous antigen was significantly lower than that using allogeneic antigen. In LMITs using 3M KCI extracts of established lymphoid cell lines, it was suggested that there were both tumor-associated antigens and leukemia-lymphoma associated antigens in the extracts. The serum immuno-suppressive factor was positive in 40 of 50 patients' sera(80%) in LMITs. The suppressive ratio and immune complex levels of the sera from patients with extensive disease was significantly higher than that of patients with localized disease. Studies on cell-mediated immunity in patients with malignant tumor.
キーワード
leukocyte migration inhibition test
malignant lymphoma
発行日
1983-08-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
95巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
721
終了ページ
729
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/95/7-8/95_7-8_721/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma