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ID 53601
フルテキストURL
著者
Takatani, Shogo Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University
Otani, Kento Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University
Kanazawa, Mai Department of Biology, Faculty of Science, Okayama University
髙橋 卓 Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University
本瀬 宏康 自然科学研究科
抄録
icrotubules are highly dynamic structures that control the spatiotemporal pattern of cell growth and division. Microtubule dynamics are regulated by reversible protein phosphorylation involving both protein kinases and phosphatases. Never in mitosis A (NIMA)-related kinases (NEKs) are a family of serine/threonine kinases that regulate microtubule-related mitotic events in fungi and animal cells (e.g. centrosome separation and spindle formation). Although plants contain multiple members of the NEK family, their functions remain elusive. Recent studies revealed that NEK6 of Arabidopsis thaliana regulates cell expansion and morphogenesis through β-tubulin phosphorylation and microtubule destabilization. In addition, plant NEK members participate in organ development and stress responses. The present phylogenetic analysis indicates that plant NEK genes are diverged from a single NEK6-like gene, which may share a common ancestor with other kinases involved in the control of microtubule organization. On the contrary, another mitotic kinase, polo-like kinase, might have been lost during the evolution of land plants. We propose that plant NEK members have acquired novel functions to regulate cell growth, microtubule organization, and stress responses.
キーワード
NIMA-related kinase
Phosphorylation
Tubulin
Microtubule
Cell expansion
Cell division
備考
The final publication is available at Springer via http://dx.doi.org/10.​1007/​s10265-015-0751-6 ,
発行日
2015-11
出版物タイトル
Journal of Plant Research
128巻
6号
出版者
Springer Japan
開始ページ
875
終了ページ
891
ISSN
0918-9440
NCID
AA10900218
資料タイプ
学術雑誌論文
言語
English
著作権者
The Botanical Society of Japan and Springer Japan
論文のバージョン
author
査読
有り
DOI
PubMed ID
Web of Sience KeyUT