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ID 30938
JaLCDOI
フルテキストURL
著者
Babazono, Akira Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University
Kitajima, Hiroyuki Department of Neonatal Medicine, Osaka Medical Center
Nishimaki, Shigeru Department of Pediatrics, Yokohama City University
Nakamura, Tomohiko Division of Neonatology, Nagano Childrenʼs Hospital, Adumino
Shiga, Seigo Neonatal Center, Juntendo University Shizuoka Hospital
Hayakawa, Masahiro Maternity and Perinatal Care Center, Nagoya University Hospital
Tanaka, Tahei Department of Pediatrics, Nagoya Daini Red Cross Hospital
Sato, Kazuo Department of Pediatrics, National Hospital Organization Kyushu Medical Center
Nakayama, Hideki Department of Neonatology, Fukuoka Childrenʼs Hospital and Medical Center for Infectious Diseases
Ibara, Satoshi Division of Neonatology, Perinatal Medical Center, Kagoshima City Hospital
Une, Hiroshi Department of Hygiene and Preventive Medicine, School of Medicine, Fukuoka University
Doi, Hiroyuki Department of Hygiene and Preventive Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
抄録

We evaluated the infection risks in the neonatal intensive care unit (NICU) using data of NICU infection surveillance data. The subjects were 871 NICU babies, consisting of 465 boys and 406 girls, who were cared for between June 2002 and January 2003 in 7 medical institutions that employed NICU infection surveillance. Infections were defined according to the National Nosocomial Infection Surveillance (NNIS) System. Of the 58 babies with nosocomial infections, 15 had methicillin-resistant Staphylococcus aureus (MRSA) infection. Multiple logistic regression analysis demonstrated that the odds ratio for nosocomial infections was significantly related to gender, birth weight and the insertion of a central venous catheter (CVC). When the birth weight group of more than 1, 500g was regarded as the reference, the odds ratio was 2.35 in the birth weight group of 1,000-1,499g and 8.82 in the birth weight group of less than 1,000g. The odds ratio of the CVC () for nosocomial infection was 2.27. However, other devices including artificial ventilation, umbilical artery catheter, umbilical venous catheter, and urinary catheter were not significant risk factors. The incidence of MRSA infection rapidly increased from 0.3% in the birth weight group of more than 1,500g to 2.1% in the birth weight group of 1,000-1,499g, and to 11.1% in the birth weight group of less than 1,000g. When the birth weight group of more than 1,500g was regarded as the reference, multiple logistic regression analysis demonstrated that the odds ratio was 7.25 in the birth weight group of 1,000-1,499g and 42.88 in the birth weight group of less than 1,000g. These odds ratios were significantly higher than that in the reference group. However, the application of devices did not cause any significant differences in the odds ratio for MRSA infection.

キーワード
risk factors
nosocomial infection
neonatal intensive care unit
JANIS
Amo Type
Original Article
発行日
2008-08
出版物タイトル
Acta Medica Okayama
62巻
4号
出版者
Okayama University Medical School
開始ページ
261
終了ページ
268
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT