JaLCDOI 10.18926/AMO/32783
フルテキストURL fulltext.pdf
著者 Ueki, Ayako| Tada, Hiroshi| Seno, Satimaru|
抄録 <p>Antigenicity of clozapine was studied in rabbits, comparing with that of chlorpromazine as control. The results indicate that chlorpromazine produces antibody in rabbit as revealed by passive hemagglutination test, giving the titer of 1 : 2, 000 or higher in all the five cases observed, though specific precipitin lines has not been obtained and PCA test proves to be negative. Clozapine failed to produce anti.clozapine antibody giving negative passive hemagglutination test, passive cutaneous anaphylaxis and precipitin reaction, in all forms tested. Some remarks were made on the possible close relation between the antigenicity of the drug and its affinity to protein.</p>
Amo Type Article
発行日 1970-06
出版物タイトル Acta Medicinae Okayama
24巻
3号
出版者 Okayama University Medical School
開始ページ 323
終了ページ 332
NCID AA00041342
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 4249889
NAID 120002311637