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ID 30942
JaLCDOI
フルテキストURL
著者
Takasaki, Yohsuke Hygiene and Preventive Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kawakami, Norito Department of Mental Health, Graduate School of Medicine and Facculty of Medicine, the University of Tokyo
Tsuchiya, Masao Hygiene and Preventive Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Ono, Yutaka Health Center, Keio University
Nakane, Yoshibumi Division of Human Sociology, Nagasaki International University Graduate School
Nakamura, Yosikazu Department of Public Health, Jichi Medical School
Tachimori, Hisateru National Institute of Mental Health, National Center of Neurology and Psychiatry
Iwata, Noboru Faculty of Human and Social Environment, Hiroshima International University
Uda, Hidenori Sensatsu Public Health Center
Nakane, Hideyuki Division of Neuropsychiatry, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences
Watanabe, Makoto Department of Psychiatry, Nagoya City University Medical School
Naganuma, Yoichi National Institute of Mental Health, National Center of Neurology and Psychiatry
Furukawa, Toshiaki Department of Psychiatry, Nagoya City University Medical School
Hata, Yukihiro Oshima Hospital
Kobayashi, Masayo Department of Public Health, Jichi Medical School
Miyake, Yuko National Institute of Mental Health, National Center of Neurology and Psychiatry
Takeshima, Tadashi National Institute of Mental Health, National Center of Neurology and Psychiatry
Kikkawa, Takehiko Chubu Gakuin University
抄録

We examined whether selected circulatory diseases (heart disease, stroke, diabetes and hypertension) were associated with an increased risk of major depression in the Japanese community population. Face-to-face household surveys were carried out in 7 areas, and a total of 2,436 persons participated (overall response rate: 58.4%) from 2002 to 2004. The WHO Composite International Diagnostic Interview 3.0 was used to diagnose major depression according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and additional interviews assessed the presence of circulatory diseases. Using data from a random subsample of the respondents (n=832), we conducted Cox proportional hazards models to calculate hazard ratios for the onset of major depression with comorbid circulatory diseases as a time-dependent covariate. Heart attack was significantly associated with the onset of major depression (hazard ratio [HR], 7.51 [95%Confidential Interval (CI), 1.36-41.45]) after adjusting for sex, birth cohort, smoking, alcohol intake, and education. Heart disease (HR, 2.12 [95% CI, 0.79-5.70]), diabetes (HR, 2.36 [95% CI, 0.42-13.34]) and hypertension (HR, 0.97 [95% CI, 0.37, 2.50]) were not significantly associated. There were no subjects who developed major depression after stroke. These results suggest that heart attack, and maybe also heart disease and diabetes, affect the onset of major depression.

キーワード
heart disease
circulatory diseases
major depression
community residents
world mental health
Amo Type
Original Article
発行日
2008-08
出版物タイトル
Acta Medica Okayama
62巻
4号
出版者
Okayama University Medical School
開始ページ
241
終了ページ
249
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT