JaLCDOI 10.18926/AMO/32458
フルテキストURL fulltext.pdf
著者 Ohmori, S.| Ubuka, T.| Shimomura, T.| Azumi, T.| Horiuchi, K.|
抄録 <p>FUKUTOME has once reported that isovaleric acid is an isovalthinuria inducer but isovaleric acid-1-C14 administered to a dog does not incorporate into urinary isovalthine and glutamic acid is most strongly labeled among acidic amino acids excreted. Recently, however, KUWAKI has found that liver homogenates of some animals can synthesize C14-labeled S-(isopropylcarboxymethyl) glutathione (GSIV) from isovaleric acid-1-C14 and glutathione, and that GSIV can be converted into isovalthine by kidney homogenate or glutathionase preparation4. For the elucidation of the above discrepancy, FUKUTOME's experiments were repeated by using isovaleric acid-methyl-C14 or-1-C14, and it was again found that these isotopic compounds did not significantly incorporate into urinary isovalthine.</p>
Amo Type Brief Note
発行日 1964-12
出版物タイトル Acta Medicinae Okayama
18巻
6号
出版者 Okayama University Medical School
開始ページ 351
終了ページ 352
NCID AA00041342
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 4221608
NAID 120002311661