JaLCDOI 10.18926/AMO/31701
フルテキストURL fulltext.pdf
著者 Willmore, L. James| Ueda, Yuto|
抄録 <p>Genetic and molecular biological methodologies are being applied to the study of patients with epilepsy at an ever-increasing pace. Accurate classification of epilepsy within large families has allowed identification of genes through linkage analysis and then isolation of gene products. Mutations causing ion channel abnormalities coupled with clinical patterns of focal epilepsy syndromes are beginning to change our thinking about the etiology of recurrent seizures in all patients. Molecular methodology is beginning to have impact on understanding of the mechanisms of actions of drugs used to treat epilepsy and will have an impact on how future treatments are designed. </p>
キーワード molecular genetic epilepsy glutamate transporter
Amo Type Review
発行日 2002-04
出版物タイトル Acta Medica Okayama
56巻
2号
出版者 Okayama University Medical School
開始ページ 57
終了ページ 68
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 12002619
Web of Science KeyUT 000175176900001