JaLCDOI 10.18926/AMO/30386
フルテキストURL fulltext.pdf
著者 Zhao, Yi| Wang, Xiaoyan| Kawai, Motoko| Liu, Jiankang| Liu, Miao| Mori, Akitane|
抄録 <p>Chinese ant extract preparations (CAEP) are a Chinese traditional medicine which is mainly used as a health food or drink for the treatment of rheumatism, rheumatoid arthritis, chronic hepatitis, sexual hypofunction, and antiaging in China. The effects on free radicals were examined by electron spin resonance spectrometry using the spin trapping agent 5.5-dimethyl-1-pyrroline-1-oxide (DMPO). Superoxide radicals (3.35 x 10(15) spins/ml) were quenched 50% by the extract at 0.5 mg/ml. The CAEP extract at 0.7 mg/ml inhibited 50% of hydroxyl radicals (52.0 x 10(15) spins/ml) generated by the Fenton reaction. Against DPPH radical, the scavenging action of CAEP was observed at 1.8 mg/ml of the extract and 50% of the DPPH radicals (8.14 x 10(15) spins/ml) were quenched. In vitro tests showed that CAEP inhibited the production of thiobarbituric acid-reactive substances, an index of lipid peroxidation, in rat brain homogenate.</p>
キーワード free radical scavenger antioxidant hydroxyl radical superoxide radical lipid peroxidation
Amo Type Article
発行日 1995-12
出版物タイトル Acta Medica Okayama
49巻
6号
出版者 Okayama University Medical School
開始ページ 275
終了ページ 279
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 8770235
Web of Sience KeyUT A1995TM84600001