JaLCDOI 10.18926/AMO/55311
フルテキストURL 71_4_341.pdf
著者 Yamazaki, Kenji| Wakabayashi, Hiroshi| Suganami, Yu| Sano, Shinichi| Wakunami, Yu| Katayama, Takashi| Deguchi, Kentaro| Nagotani, Shoko| Kishida, Masayuki|
抄録 We report a case of a woman with typical dermatomyositis (DM) with skin manifestations, severe myalgia and muscle weakness complicated by interstitial lung disease (ILD) and pneumomediastinum. Pneumomediastinum persisted despite treatment with immunosuppressive therapy (steroids and cyclosporine). After the test for anti-melanoma differentiation-associated gene 5 (MDA5) antibody came out positive, we doubled the cyclosporine dose and her condition improved. Despite typical clinical features of DM, in cases complicated by pneumomediastinum or steroid resistance, measurement of anti-MDA5 antibody may be useful for immunosuppressant dose titration.
キーワード dermatomyositis anti-melanoma differentiation-associated gene 5 antibody interstitial lung disease pneumomediastinum
Amo Type Case Report
発行日 2017-08
出版物タイトル Acta Medica Okayama
71巻
4号
出版者 Okayama University Medical School
開始ページ 341
終了ページ 344
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28824190