JaLCDOI 10.18926/AMO/32781
フルテキストURL fulltext.pdf
著者 Yamamoto, Yasuhisa| Jituiki, Dairoku| Yabuki, Yasuo|
抄録 <p>Antigenicity of the peptide of ribosomal digest in Ehrlich ascites tumor was studied. The peptide was purified by DEAE Sephadex A-50 column chromatography. The peptide was electrophoretically basic, single, and 1.32 S20w sedimentation coefficient with poor content of tyrosine and phenylalanine. The maximum absorbancy was at 267 m&#956;. Mice and rabbits were immunized with the mixture of the purified peptide with Freund's complete adjuvant. The inhibitory effect of immune &#947;-globulin on the tumor growth was demonstrated in vitro cultured JTC-11 cells. A single precipitin line was observed between rabbit antiserum and tumor cell extract of Ehrlich ascites cells in ouchterlony double diffusion chamber and immunoelectrophoresis. The sedimentation coefficient of the effective fraction in immune-serum was 17 S20w. The precipitin line was observed at &#946;2-&#947; region in immunoelectrophoresis.</p>
Amo Type Article
発行日 1970-10
出版物タイトル Acta Medicinae Okayama
24巻
5号
出版者 Okayama University Medical School
開始ページ 537
終了ページ 547
NCID AA00041342
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 4256472
NAID 120002311715