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ID 16462
Eprint ID
16462
フルテキストURL
Thumnail 93_25.pdf 595 KB
タイトル(別表記)
Donaggio reaction positive substances derived from serum protein (Cohn fraction VI)
著者
大森 祥夫 岡山大学医学部公衆衛生学教室
抄録
Up to date Donaggio reaction positive substances derived from serum protein have been shown to be from the α(1)-globulin region, mainly α(1)-AG. One purpose of this study was to purify α(1)-AG from Cohn fraction VI of human serum by means of starch block electrophoresis and to measure the Donaggio titer in it. The other purpose was to compare α(1)-AG with the other protein subfraction. The results were: 1) Pure (about 98%) α(1)-AG was obtained from Cohn fraction VI after heating. The Donaggio titer of α(1)-AG solution was 1.7-2.2/mg/dl. Whole Cohn fraction VI was 1.2, human albumin was 0.7 and α(2)-HS was 0.8. 2) The Donaggio specific activity was indirectly proved to be in the order of α(1)-globulin>α(2)-globulin contained in the Cohn fraction VI. This result supports the previous report. 3) A solution of Cohn fraction VI was almost equal in Donaggio titer per the same concentration of protein to urine after exercise, after treatment by heating at 100℃ for 10 minutes and acidification to pH. 5 by acetic acid. 4) α(1)-AG was concluded to have the highest Donaggio titer of the whole protein subfraction.
キーワード
Donaggio反応
Cohn fraction VI
α(1)-acid glycoprotein
発行日
1981-02-28
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
93巻
1-2号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
25
終了ページ
30
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/93/1-2/93_1-2_25/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma