start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=643
end-page=656
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Enzymological studies on rheumatoid arthritis. 1. Studies on collagenase and monoamine-oxidase activities in patients with rheumatoid arthritis
kn-title=慢性関節リウマチにおける酵素学的研究 第1編 慢性関節リウマチのコラゲナーゼ活性ならびにモノアミンオキシダーゼ活性について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We assayed the activities of collagenase and monoamine-oxidase (MAO) in the fluid of the patients with rheumatoid arthritis (RA) and examined the relationship between collagenase, MAO activities and the grade of joint inflammation. The mean collagenase value of RA patients was significantly higher than that of osteoarthritis (OA) patients. A significant positive correlation was present between collagenase activity, leukocyte counts, and beta-glucuronidase activity in RA synovial fluid. These indices are considered to be parameters of the grade of joint inflammation. There was no correlation between collagenase activity, erythrocyte sedimentation rate (ESR), gamma-globulin level, C-reactive protein (CRP), rheumatoid factor, acid-phosphatase activity and the stage of RA (grade of joint destruction). The mean MAO value of RA synovial fluid was significantly higher than that of OA synovial fluid. The mean activity of the group of patients whose CRP values were below two positive was significantly higher than that of the group of patients whose CRP values were over two positive. The mean MAO activity in stage 3 or 4 group was significantly higher than that in stage 1 or 2. These findings suggest that collagenase activity is intimately correlated with the grade of local Inflammation in RA and that the MAO activity is closely correlated with the grade of joint fibrosis.
en-copyright=
kn-copyright=

en-aut-name=TodaShunsuke
en-aut-sei=Toda
en-aut-mei=Shunsuke
kn-aut-name=戸田俊介
kn-aut-sei=戸田
kn-aut-mei=俊介
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第三内科
en-keyword=慢性関節リウマチ
kn-keyword=慢性関節リウマチ
en-keyword=コラゲナーゼ活性
kn-keyword=コラゲナーゼ活性
en-keyword=モノアミンオキシダーゼ活性
kn-keyword=モノアミンオキシダーゼ活性
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=657
end-page=666
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Enzymological studies on rheumatoid arthritis. 2. Relationship between collagenase activity and the clinical course of patients with rheumatoid arthritis
kn-title=慢性関節リウマチにおける酵素学的研究 第2編 慢性関節リウマチの経過とコラゲナーゼ活性
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We examined the relationship between collagenase activity and the clinical course of the patients with rheumatoid arthritis (RA). The activity of active and inactive collagenase (treated by 3M-KI) was assayed several times for synovial fluid from twelve RA patients and one patient with osteoarthritis (OA). Rheumatoid factor, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), leukocyte counts and acid-phosphatase activity in the synovial fluid were measured simultaneously. In seven of twelve cases, the change of inactive collagenase activity was parallel by changes in synovial leukocyte counts or acid-phosphatase activity. In five of seven cases, the change in inactive collagenase activity was paralleled by acid-phosphatase activity and leukocyte counts. These findings suggest that collagenase activity is intimately correlated with the grade of local inflammation of RA and that the change of collagenase activity is closely correlated with the clinical course of RA patients.
en-copyright=
kn-copyright=

en-aut-name=TodaShunsuke
en-aut-sei=Toda
en-aut-mei=Shunsuke
kn-aut-name=戸田俊介
kn-aut-sei=戸田
kn-aut-mei=俊介
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第三内科教室
en-keyword=慢性関節リウマチ
kn-keyword=慢性関節リウマチ
en-keyword=コラゲナーゼ活性
kn-keyword=コラゲナーゼ活性
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=667
end-page=683
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=CYTOLOGICAL STUDIES ON BRONCHOALVEOLAR LAVAGE FLUID IN BRONCHIAL ASTHMA
kn-title=気道細胞反応からみた呼吸器疾患の研究 第1編 気管支肺胞洗浄法による気管支喘息の病態に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Cytological studies were performed on bronchoalvelar lavage(BAL) fluid in 40 cases with bronchial asthma. The results were as follows. 1) In 13 healthy subjects the cells in BAL fluid comprised 89.6% macrophages, 9.7% lymphocytes, 0.7% neutrophils, 0.4% eosinophils and 0% basophils. 2) In asthmatic cases the cells in BAL fluid comprised 54.4% macrophages, 12.6% lymphocytes, 11.8% neutrophils, 21.2% eosinophils and 0.1% basophils. These cases showed a marked increase in the number of eosinophils and a moderate increase in the neutrophil count as compared with healthy subjects. The increased number of eosinophils in lavage fluid was relatively closely related to positive immediate skin tests, high serum IgE levels and peripheral eosinophilia. As for asthmatic types, this was marked in the atopic type. By contrast, an increased number of neutrophils in the lavage fluid was frequently found in non-atopic or intractable asthmatics showing the frequent complication of peripheral airway disorder in pulmonary function tests. Therefore, it seems that the present study gave much information on the characteristics and the etiology of the intractable asthmatics. 3) Eosinophils in BAL fluid reflected the appearance of eosinophils in the alveolar spaces and eosinophil infiltration into the septa in the histological findings. On the other hand, neutrophils could be observed clearly by the BAL method even when they could not be observed clearly by histological studies. In conclusion, the cytological studies performed on BAL fluid are considered useful in the diagnosis of bronchial asthma, especially for the classification into subtypes of asthma.
en-copyright=
kn-copyright=

en-aut-name=TakeyamaHiroyasu
en-aut-sei=Takeyama
en-aut-mei=Hiroyasu
kn-aut-name=竹山博泰
kn-aut-sei=竹山
kn-aut-mei=博泰
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科学教室
en-keyword=bronchoalveolar lavage
kn-keyword=bronchoalveolar lavage
en-keyword=bronchial asthma
kn-keyword=bronchial asthma
en-keyword=eosinophils
kn-keyword=eosinophils
en-keyword=neutrophils
kn-keyword=neutrophils
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=685
end-page=700
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=CYTOLOGICAL STUDIES ON BRONCHOALVEOLAR LAVAGE FLUID IN INFLAMMATORY AND GRANULOMATOUS RESPIRATORY DISEASES
kn-title=気道細胞反応からみた呼吸器疾患の研究 第2編 気管支肺胞洗浄法による炎症性・肉芽腫性疾患の病態に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Cytological studies were performed on bronchoalveolar lavage(BAL) fluid in 7 cases with hypersensitivity pneumonitis, 6 with sarcoidosis, 6 with chronic bronchitis and 5 with bronchiolitis. In the cases with hypersensitivity pneumonitis and bronchiolitis, cytological studies of BAL fluid were compared with the histological findings of lungs. Furthermore, animal models of hypersensitivity pneumonitis were made and examined likewise. The results were as follows. 1) In the cases with hypersensitivity pneumonitis, a marked increase in the lymphocyte count in BAL fluid was characteristic. These cases showed an increase in the percentage of T lymphocytes in BAL fluid as compared with healthy subjects. In the cases with sarcoidosis, an increase in the number of lymphocytes was also found and especially the ratio of the percentage of T lymphocytes to that of B lymphocytes was much higher than those of the other diseases and healthy subjects. 2) An increased number of neutrophils in BAL fluid was observed in the cases with chronic bronchitis. In the cases with bronchiolitis, a marked increase in the neutrophil count was characteristic. 3) A common histological finding in hypersensitivity pneumonitis was mononuclear cell infiltration into alveolar septa and most of the cells in BAL fluid were lymphocytes. In bronchiolitis, mononuclear cell infiltration into and around the bronchiolar walls was found commonly and neutrophils were found increased in BAL fluid. 4) In experimental hypersensitivity pneumonitis, mononuclear cell infiltration into septa closely paralleled the lymphocyte appearance in BAL fluid.
en-copyright=
kn-copyright=

en-aut-name=TakeyamaHiroyasu
en-aut-sei=Takeyama
en-aut-mei=Hiroyasu
kn-aut-name=竹山博泰
kn-aut-sei=竹山
kn-aut-mei=博泰
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科学教室
en-keyword=bronchoalveolar lavage
kn-keyword=bronchoalveolar lavage
en-keyword=hypersensitivity pneumonitis
kn-keyword=hypersensitivity pneumonitis
en-keyword=sarcoidosis
kn-keyword=sarcoidosis
en-keyword=chronic bronchitis
kn-keyword=chronic bronchitis
en-keyword=bronchiolitis
kn-keyword=bronchiolitis
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=709
end-page=715
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on cell fusion by C-type viruses
kn-title=C型ウイルスによる細胞融合の研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1. Autoradiographic study of syncytium formation between rat XC cells and MuLV-producing cells indicated that the syncytium consisted of XC cells exclusively. Virusproducing cells did not coexist with XC cells in the syncytium. 2. Human cells which formed a syncytium in response to SSAV or BaEV were transformed cells and were not normal cells. SSAV induced over a narrower range of human transformed cells than BaEV. In nonhuman cultured cells, BaEV did not induce a syncytium at all as far as tested. On the other hand, SSAV induced a syncytium in XC, GMK and CV-I cells. Anti-SSAV serum specifically blocked syncytium formation by SSAV but not by BaEV. Similarly anti-BaEV serum specifically blocked syncytium formation by BaEV but not by SSAV. Therefore, syncytium formation is specific for each virus and there is no cross-neutralization between SSAV and BaEV.
en-copyright=
kn-copyright=

en-aut-name=OchoMunehiko
en-aut-sei=Ocho
en-aut-mei=Munehiko
kn-aut-name=大重宗比古
kn-aut-sei=大重
kn-aut-mei=宗比古
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部癌源研究施設生化学部門
en-keyword=細胞融合
kn-keyword=細胞融合
en-keyword=マウス白血病ウイルス
kn-keyword=マウス白血病ウイルス
en-keyword=ヒヒ内在性ウイルス
kn-keyword=ヒヒ内在性ウイルス
en-keyword=サル内腫ウイルス
kn-keyword=サル内腫ウイルス
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=717
end-page=727
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Electrocardiographic changes after neurosurgery
kn-title=脳外科手術前後における心電図変化
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Electrocardiograms (ECG) and laboratory data were studied in 130 neurosurgical patients before and after neurosurgery. The following results were obtained: 1. The postoperative ECG showed ST-T changes in 21 % of the cases with subarachnoid hemorrhage, 15 % with cerebral tumor, 37.5 % with supracellar tumor and 50 % with Parkinson syndrome. 2. In 50 % of subarachnoid hemorrhage and 47 % of cerebral tumor, postoperative ECG deteriorated within 1 week. After 2 weeks such deterioration was observed in only 37 % in the former cases and 43 % in the latter. 3. Postoperative ECGs were improved or unchanged in 83 % cases of cerebral bleeding, 75 % (within 1 week) and 83 % (after 2 weeks) of intracerebral bleeding, and in all of Parkinson syndrome. However, in the cases of supra-cellar tumor, postoperative ECGs deteriorated 100 % within 1 week and 75 % after 2 weeks. 4. Serum K(+) and Ca(++) were decreased significantly in the group with deteriorated postoperative ECGs. The R. B. C., Hb and Ht were decreased regardless of postoperative ECGs. 5. Postoperative ECGs deteriorated when the operation time lasted longer than 6 h or blood loss during the operation was over 1,000 ml.
en-copyright=
kn-copyright=

en-aut-name=YoshidaHidenori
en-aut-sei=Yoshida
en-aut-mei=Hidenori
kn-aut-name=吉田英紀
kn-aut-sei=吉田
kn-aut-mei=英紀
aut-affil-num=1
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=斉藤大治
kn-aut-sei=斉藤
kn-aut-mei=大治
aut-affil-num=2
ORCID=

en-aut-name=HyodoTazuo
en-aut-sei=Hyodo
en-aut-mei=Tazuo
kn-aut-name=兵頭多津男
kn-aut-sei=兵頭
kn-aut-mei=多津男
aut-affil-num=3
ORCID=

en-aut-name=NishiharaMasanobu
en-aut-sei=Nishihara
en-aut-mei=Masanobu
kn-aut-name=西原正信
kn-aut-sei=西原
kn-aut-mei=正信
aut-affil-num=4
ORCID=

en-aut-name=UchidaToshiaki
en-aut-sei=Uchida
en-aut-mei=Toshiaki
kn-aut-name=内田俊明
kn-aut-sei=内田
kn-aut-mei=俊明
aut-affil-num=5
ORCID=

en-aut-name=KimuraMasashi
en-aut-sei=Kimura
en-aut-mei=Masashi
kn-aut-name=木村正司
kn-aut-sei=木村
kn-aut-mei=正司
aut-affil-num=6
ORCID=

en-aut-name=TakedaKou
en-aut-sei=Takeda
en-aut-mei=Kou
kn-aut-name=武田光
kn-aut-sei=武田
kn-aut-mei=光
aut-affil-num=7
ORCID=

en-aut-name=FujiiAkinobu
en-aut-sei=Fujii
en-aut-mei=Akinobu
kn-aut-name=藤井章伸
kn-aut-sei=藤井
kn-aut-mei=章伸
aut-affil-num=8
ORCID=

en-aut-name=NagahanaHaruki
en-aut-sei=Nagahana
en-aut-mei=Haruki
kn-aut-name=長花晴樹
kn-aut-sei=長花
kn-aut-mei=晴樹
aut-affil-num=9
ORCID=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=原岡昭一
kn-aut-sei=原岡
kn-aut-mei=昭一
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部第一内科教室

affil-num=10
en-affil=
kn-affil=岡山大学医学部附属病院中央検査部
en-keyword=クモ膜下出血
kn-keyword=クモ膜下出血
en-keyword=術後心電図
kn-keyword=術後心電図
en-keyword=脳外科手術
kn-keyword=脳外科手術
en-keyword=脳性T波
kn-keyword=脳性T波
en-keyword=カテコールアミン
kn-keyword=カテコールアミン
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=729
end-page=738
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A survey of Danshukai members in Okayama Prefecture
kn-title=岡山県における断酒会会員の実態調査
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A survey of Danshukai (Alcohol Abstinence Society) members was conducted in Okayama Prefecture, November, 1978. It was based on selfcompletion quetionaircs given to members attending the meetings of Okayama and Tsuyama Danshukai. Out of 290 resistered members, 202 attendants gave answers to the quetionaires (response rate: 69.7%). All of the respondents were male alcoholics. Among them, 80.6% were married, 81.2% had jobs, and 82.7% were accompanied by their wives or other family members in the meetings. This favorable family situation was in sharp contrast to that of long-term inpatient alcoholics. Admission to the Department of Psychiatry had been experienced by 63.9% of attendants and 17.3% to the Department of Internal Medicine. Many of the patients had been introduced to Danshukai by hospital staff and the activities of Danshukai were largely supported by psychiatric hospitals. In future, however, Danshukai must be more independent, establishing good relationships with community health centers or other local agencies. This means the development from a hospital-based Danshukai to a community-based one. This survey also suggested that intervention at an early stage of alcoholism is needed when alcohol-related impairment is limited to occasional violence at home. At this satage, spouses and Danshukai members might have important therapeutic roles. Regular attendance at Danshukai meetings at least once a week or twice a month seemed indispensable for continued abstinence.
en-copyright=
kn-copyright=

en-aut-name=TakahashiS.
en-aut-sei=Takahashi
en-aut-mei=S.
kn-aut-name=高橋茂
kn-aut-sei=高橋
kn-aut-mei=茂
aut-affil-num=1
ORCID=

en-aut-name=HoriiS.
en-aut-sei=Horii
en-aut-mei=S.
kn-aut-name=堀井茂男
kn-aut-sei=堀井
kn-aut-mei=茂男
aut-affil-num=2
ORCID=

en-aut-name=FujimotoA.
en-aut-sei=Fujimoto
en-aut-mei=A.
kn-aut-name=藤本明
kn-aut-sei=藤本
kn-aut-mei=明
aut-affil-num=3
ORCID=

en-aut-name=SuwakiH.
en-aut-sei=Suwaki
en-aut-mei=H.
kn-aut-name=洲脇寛
kn-aut-sei=洲脇
kn-aut-mei=寛
aut-affil-num=4
ORCID=

en-aut-name=NishiiY.
en-aut-sei=Nishii
en-aut-mei=Y.
kn-aut-name=西井保行
kn-aut-sei=西井
kn-aut-mei=保行
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部神経精神医学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部神経精神医学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部神経精神医学教室

affil-num=4
en-affil=
kn-affil=高知医科大学神経精神医学教室

affil-num=5
en-affil=
kn-affil=高知医科大学神経精神医学教室
en-keyword=アルコール症
kn-keyword=アルコール症
en-keyword=断酒会
kn-keyword=断酒会
en-keyword=実態調査
kn-keyword=実態調査
en-keyword=岡山県
kn-keyword=岡山県
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=739
end-page=748
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on antitumor activity of interferon 1. Effect of interferon on human hematopoietic cell lines grown in vitro
kn-title=インターフェロンの抗腫瘍性に関する研究 第1編 In vitroにおけるヒト造血腫瘍細胞株の増殖に及ぼすインターフェロンの効果
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A total of 12 hematopoietic cell lines was tested for in vitro sensitivity to interferon (IF). The cell lines were 4 T-cell ALL lines (TALL-1, MOLT-4, HPB-ALL, HSB-2), 1 ATL line (MT-1), 2 null-cell ALL lines (NALL-1, KOPN-8), 1 pre-B-cell ALL line (NALM-18), 1 B-cell line (BALL-1), 1 myeloma line (Oda), 1 Burkitt lymphoma line (JBL-3) and 1 APL line (HL-60). At a concentration of 1,000 U/ml, all 4 T-cell ALL lines, NALM-18, NALL-1 and Oda showed high or moderate sensitivity to the growth inhibition effect of IF. BALL-1 showed slight sensitvity and its in vitro growth was considerably inhibited at a higher concentration of IF (5,000 U/ml). However, MT-1, JBL-3, KOPN-8 and HL-60 were resistant to IF and their in vitro growth was not inhibited at all even at the concentration of 1,000 U/ml. MT-1 cells, although resistant to IF in suspension culture, were sensitive in agar culture. Colony formation was markedly inhibited at a concentration of 1,000 U/ml. The mechanism of growth inhibition by IF and the implications of the present findings are discussed.
en-copyright=
kn-copyright=

en-aut-name=LaiMiinyuh
en-aut-sei=Lai
en-aut-mei=Miinyuh
kn-aut-name=頼敏裕
kn-aut-sei=頼
kn-aut-mei=敏裕
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第2内科教室
en-keyword=Interferon
kn-keyword=Interferon
en-keyword=Antitumor activity
kn-keyword=Antitumor activity
en-keyword=Hematopoietic
kn-keyword=Hematopoietic
en-keyword=cell lines
kn-keyword=cell lines
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=749
end-page=753
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Tuberculoid leprosy. Report of two cases
kn-title=Tuberculoid leprosyの二症例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Tuberculoid leprosy in a 69 year-old and a 72 year-old man is presented, because the disease seems rare recently. From the experience of these cases, the importance of attention to the disease, in the everyday medical examination even today was emphasized.
en-copyright=
kn-copyright=

en-aut-name=SonobeHiroshi
en-aut-sei=Sonobe
en-aut-mei=Hiroshi
kn-aut-name=園部宏
kn-aut-sei=園部
kn-aut-mei=宏
aut-affil-num=1
ORCID=

en-aut-name=MasudaTsutomu
en-aut-sei=Masuda
en-aut-mei=Tsutomu
kn-aut-name=益田勤
kn-aut-sei=益田
kn-aut-mei=勤
aut-affil-num=2
ORCID=

en-aut-name=HiramatsuHiroko
en-aut-sei=Hiramatsu
en-aut-mei=Hiroko
kn-aut-name=平松博子
kn-aut-sei=平松
kn-aut-mei=博子
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=高知県立中央病院・癌研究所

affil-num=2
en-affil=
kn-affil=岡山赤十字病院・皮膚科

affil-num=3
en-affil=
kn-affil=岡山赤十字病院・皮膚科
en-keyword=類結核癩
kn-keyword=類結核癩
END

start-ver=1.4
cd-journal=joma
no-vol=93
cd-vols=
no-issue=7-8
article-no=
start-page=701
end-page=708
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1981
dt-pub=19810830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Multiple polypoid filling defects of the duodenal bulb
kn-title=十二指腸球部多発陰影欠損について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Multiple polypoid filling defects of the duodenal bulb are infrequently encountered. Two cases of multiple filling defects of the duodenal bulb are reported in this paper. Case 1. A 42 year old female complained of abdominal fullness and epigastralgia. On examination, generalized peripheral lymphadenopathy and marked hepatosplenomegaly were noted. Cervical lymphnode biopsy revealed a diffuse, poorly-differanciated lymphocytic lymphoma. X-ray examination of the gastrointestinal tract showed multiple filling defects localized at the duodenal bulb. Endoscopy disclosed multiple well-defined protrusions with small mucosal ulceration over the the whole circumference of the duodenal wall. Case 2. A 36 year old female had no subjective symptoms. At gastric mass screening, numerous polypoid elevations of the duodenal bulb were pointed out. Detailed gastrointestinal x-ray examination showed numerous, tiny, round polypoid nodules localized at the duodenal bulb. These nodules were 2-3mm in size with no mucosal ulceration. The endoscopic biopsy specimen revealed lymphoid hyperplasia of the duodenal bulb.
en-copyright=
kn-copyright=

en-aut-name=MorinoYasuo
en-aut-sei=Morino
en-aut-mei=Yasuo
kn-aut-name=森野靖雄
kn-aut-sei=森野
kn-aut-mei=靖雄
aut-affil-num=1
ORCID=

en-aut-name=TakedaYoshihiro
en-aut-sei=Takeda
en-aut-mei=Yoshihiro
kn-aut-name=竹田芳弘
kn-aut-sei=竹田
kn-aut-mei=芳弘
aut-affil-num=2
ORCID=

en-aut-name=MorimotoSetsuo
en-aut-sei=Morimoto
en-aut-mei=Setsuo
kn-aut-name=森本節夫
kn-aut-sei=森本
kn-aut-mei=節夫
aut-affil-num=3
ORCID=

en-aut-name=MiyakeMasayoshi
en-aut-sei=Miyake
en-aut-mei=Masayoshi
kn-aut-name=三宅正淑
kn-aut-sei=三宅
kn-aut-mei=正淑
aut-affil-num=4
ORCID=

en-aut-name=HayashiHidehiro
en-aut-sei=Hayashi
en-aut-mei=Hidehiro
kn-aut-name=林英博
kn-aut-sei=林
kn-aut-mei=英博
aut-affil-num=5
ORCID=

en-aut-name=EzoeHiroshi
en-aut-sei=Ezoe
en-aut-mei=Hiroshi
kn-aut-name=江添弘
kn-aut-sei=江添
kn-aut-mei=弘
aut-affil-num=6
ORCID=

en-aut-name=KimotoShin
en-aut-sei=Kimoto
en-aut-mei=Shin
kn-aut-name=木本真
kn-aut-sei=木本
kn-aut-mei=真
aut-affil-num=7
ORCID=

en-aut-name=JojaIkuo
en-aut-sei=Joja
en-aut-mei=Ikuo
kn-aut-name=上者郁夫
kn-aut-sei=上者
kn-aut-mei=郁夫
aut-affil-num=8
ORCID=

en-aut-name=HashimotoKeiji
en-aut-sei=Hashimoto
en-aut-mei=Keiji
kn-aut-name=橋本啓二
kn-aut-sei=橋本
kn-aut-mei=啓二
aut-affil-num=9
ORCID=

en-aut-name=AonoKaname
en-aut-sei=Aono
en-aut-mei=Kaname
kn-aut-name=青野要
kn-aut-sei=青野
kn-aut-mei=要
aut-affil-num=10
ORCID=

en-aut-name=HayashiKyoichi
en-aut-sei=Hayashi
en-aut-mei=Kyoichi
kn-aut-name=林恭一
kn-aut-sei=林
kn-aut-mei=恭一
aut-affil-num=11
ORCID=

en-aut-name=TakaokaKazuko
en-aut-sei=Takaoka
en-aut-mei=Kazuko
kn-aut-name=高岡和子
kn-aut-sei=高岡
kn-aut-mei=和子
aut-affil-num=12
ORCID=

en-aut-name=OshimaYukiko
en-aut-sei=Oshima
en-aut-mei=Yukiko
kn-aut-name=大島由起子
kn-aut-sei=大島
kn-aut-mei=由起子
aut-affil-num=13
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=8
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=9
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=10
en-affil=
kn-affil=岡山大学医学部放射線医学教室

affil-num=11
en-affil=
kn-affil=岡山大学医学部第II内科学教室

affil-num=12
en-affil=
kn-affil=岡山大学医学部第II内科学教室

affil-num=13
en-affil=
kn-affil=三菱水島病院内科
en-keyword=Duodenal bulb
kn-keyword=Duodenal bulb
en-keyword=multiple polypoid nodules
kn-keyword=multiple polypoid nodules
END