このエントリーをはてなブックマークに追加
ID 45273
JaLCDOI
フルテキストURL
65_2_135.pdf 5.41 MB
著者
Matsuo, Toshihiko Departments of Ophthalmology, Okayama University Medical School and Graduate School of Medicine, Dentistry and Pharmaceutical Sciences ORCID Kaken ID publons researchmap
Himei, Kengo
Ishii, Keita Department of Medicine, Chugoku Central Hospital
Nose, Soichiro Department of Pathology, Okayama Saiseikai General Hospital
Mimura, Tetsushige Departments of Surgery, Okayama Saiseikai General Hospital
抄録
An 18-year-old woman with a 2-year history of hypertension and headache was diagnosed with noradrenalin-secreting bilateral adrenal pheochromocytomas with paragangliomas in the background of von Hippel-Lindau disease with family histories and a missense mutation, 712C to T (Arg167Trp) in the VHL gene. She had optic disc hemangioma in the left eye which gradually enlarged and caused serous retinal detachment on the macula in one year. Low-dose external beam radiation (20 Gy) was administered to the left eye using a lens-sparing single lateral technique. She underwent craniotomy for cerebellar hemangioblastoma at the age of 22 years and total pancreatectomy for multiple neuroendocrine tumors at the age of 24 years. In the 6-year follow-up period after the radiotherapy, the optic disc hemangioma gradually reduced in size and its activity remained low, allowing good central vision to be maintained. External beam radiation is recommended as a treatment option for the initial therapy for optic disc hemangioma.
キーワード
retinal (papillary, optic disc) hemangioma
von Hippel-Lindau disease
pheochromocytoma
pancreatic neuroendocrine tumor
external beam radiation (radiotherapy)
Amo Type
Case Report
発行日
2011-04
出版物タイトル
Acta Medica Okayama
65巻
2号
出版者
Okayama University Medical School
開始ページ
135
終了ページ
141
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT