JaLCDOI 10.18926/AMO/55444
フルテキストURL 71_5_445.pdf
著者 Katsuyama, Eri| Wakabayashi, Hiroshi| Sada, Ken-ei| Hiramatsu, Sumie| Miyawaki, Yoshia| Morishita, Michiko| Ohashi, Keiji| Watanabe, Haruki| Katsuyama, Takayuki| Zeggar, Sonia| Narazaki, Mariko| Tatebe, Noriko| Watanabe, Katsue S.| Kawabata, Tomoko| Wada, Jun|
抄録 We herein present a case of a 38-year-old man who had bamboo spine and severe sacroiliitis and who was diagnosed with ankylosing spondylitis (AS). Infliximab (IFX) markedly improved the axial symptom but was discontinued due to the side effect of peripheral neuropathy. Switching from IFX to etanercept worsened the side effect. Rituximab (RTX) administration elicited a good response without side effects. RTX might be a suitable option for AS therapy when TNF inhibitors are difficult to use.
キーワード ankylosing spondylitis rituximab treatment
Amo Type Case Report
発行日 2017-10
出版物タイトル Acta Medica Okayama
71巻
5号
出版者 Okayama University Medical School
開始ページ 445
終了ページ 448
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29042704
フルテキストURL Mod_Rheumatol_26_5_730.pdf
著者 Sada, Ken-ei| Harigai, Masayoshi| Amano, Koichi| Atsumi, Tatsuya| Fujimoto, Shouichi| Yuzawa, Yukio| Takasaki, Yoshinari| Banno, Shogo| Sugihara, Takahiko| Kobayashi, Masaki| Usui, Joichi| Yamagata, Kunihiro| Homma, Sakae| Dobashi, Hiroaki| Tsuboi, Naotake| Ishizu, Akihiro| Sugiyama, Hitoshi| Okada, Yasunori| Arimura, Yoshihiro| Matsuo, Seiichi| Makino, Hirofumi|
キーワード Antineutrophil cytoplasmic antibody-associated vasculitis Eosinophilic granulomatosis with polyangiitis Granulomatosis with polyangiitis Inception cohort Microscopic polyangiitis
備考 This is an Accepted Manuscript of an article published by Taylor & Francis Group
発行日 2016-03-11
出版物タイトル Modern Rheumatology
26巻
5号
出版者 Taylor & Francis
開始ページ 730
終了ページ 737
ISSN 1439-7595
NCID AA1157187X
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 26873424
DOI 10.3109/14397595.2016.1140274
Web of Sience KeyUT 000393120600018
関連URL https://doi.org/10.3109/14397595.2016.1140274
タイトル(別表記) Hospital and clinic cooperation for the treatment of rheumatoid arthritis in Okayama Prefecture, Japan
フルテキストURL 126_209.pdf
著者 佐田 憲映| 西田 圭一郎| 山中 隆夫| 三崎 健太| 若林 宏| 篠田 潤子| 髙木 徹| 矢野 隆介| 中村 明彦| 難波 良文| 守田 吉孝| 小山 芳伸| 山本 惠嗣| 江澤 和彦| 太田 裕介| 吉原 由樹| 三好 信也| 棗田 将光| 臼井 正明| 吉永 泰彦| 林 充| 山村 昌弘| 橋詰 博行|
抄録 Objective: To survey the current status and problems of cooperation between clinics and hospitals in Okayama Prefecture, Japan for the treatment of rheumatoid arthritis (RA).  Methods: We distributed a questionnaire to 300 of the 983 Okayama Prefecture clinics that had either an internal medicine or orthopedic surgery department, from December 2013 to February 2014. The questionnaire covered practice pattern for RA treatment in clinics, current status of the hospital and clinic cooperation, and acceptance of the biologic therapy.  Results: One hundred clinics responded to the questionnaire. Seventy percent of the clinics reported making referrals to rheumatologists before the initiation of RA treatment, and half of the other 30% of the clinics administered methotrexate as the first-line treatment for RA by their own decision. Sixty-six clinics cooperated with flagship hospitals, conducting medical and laboratory examinations, providing prescriptions, and treating common diseases of patients. These clinics expected the cooperating rheumatologists to follow-up patients every 3 to 6 months and to make the diagnosis, make decisions regarding RA treatment changes, and perform surgery. Seventy-one percent of the clinics responded that cooperation with a hospital is possible even for patients who are administered biologics. As reasons for no cooperation with the flagship hospitals, clinics noted the lack of information about rheumatologists in the area and recent trends in the management of RA.  Conclusion: The current study reported, for the first time, the actual conditions of management of RA in clinics, as well as future problems of hospital and clinic cooperation in Okayama Prefecture.
キーワード 病診連携(hospital and clinic cooperation) 関節リウマチ(rheumatoid arthritis) 生物学的製剤(biologics) メトトレキサート(methotrexate)
出版物タイトル 岡山医学会雑誌
発行日 2014-12-01
126巻
3号
開始ページ 209
終了ページ 215
ISSN 0030-1558
言語 Japanese
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.209
NAID 130004903246
著者 Sugiyama, Koichi| Sada, Ken-ei| Kurosawa, Michiko| Wada, Jun| Makino, Hirofumi|
発行日 2013-02
出版物タイトル Clinical and Experimental Nephrology
17巻
1号
資料タイプ 学術雑誌論文
著者 Kagawa, Hidetoshi| Hiromasa, Tsutomu| Hara, Takayuki| Takaki, Ayako| Yamanaka, Ryutaro| Sada, Ken-ei| Makino, Hirofumi|
発行日 2012-10
出版物タイトル Clinical and Experimental Nephrology
16巻
5号
資料タイプ 学術雑誌論文
著者 Takano, Mariko| Otsuka, Fumio| Matsumoto, Yoshinori| Inagaki, Kenichi| Takeda, Masaya| Nakamura, Eri| Tsukamoto, Naoko| Miyoshi, Tomoko| Sada, Ken-ei| Makino, Hirofumi|
発行日 2012-01-02
出版物タイトル Molecular and Cellular Endocrinology
348巻
1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/47015
フルテキストURL 65_5_329.pdf
著者 Matsumoto, Yoshinori| Sada, Ken-ei| Takano, Mariko| Toyota, Noriko| Yamanaka, Ryutaro| Sugiyama, Koichi| Wakabayashi, Hiroshi| Kawabata, Tomoko| Otsuka, Fumio| Makino, Hirofumi|
抄録 It is well known that infection is one of the major causes of morbidity and mortality in rheumatic disease patients treated with high-dose glucocorticoids, especially in the early phase after achievement of disease remission. The aim of this study was to identify the risk factors for infection, with a focus on the dose of glucocorticoids administered, following the achievement of disease remission in rheumatic diseases patients. We retrospectively analyzed the medical records of rheumatic disease patients who had been treated with glucocorticoids. The primary endpoint was the incidence rate of infection during a period from 1 to 2 months after the commencement of treatment. From April 2006 to March 2010, 19 of 92 patients suffered from infection during the observation period. Age≧65 yrs, presence of interstitial pneumonia, diagnosis of systemic vasculitis and serum creatinine level≧2.0mg/dl were found to be univariate predictors for infection. However, only the presence of interstitial pneumonia was an independent risk factor for infection (HR=4.50, 95%CI=1.65 to 14.44) by the Cox proportional hazard model. Even after achievement of clinical remission, careful observation is needed for patients with interstitial pneumonia, more so than for those receiving high-dose glucocorticoids.
キーワード infection rheumatic disease glucocorticoids interstitial pneumonia risk factors
Amo Type Original Article
発行日 2011-10
出版物タイトル Acta Medica Okayama
65巻
5号
出版者 Okayama University Medical School
開始ページ 329
終了ページ 334
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037270
Web of Sience KeyUT 000296116400007
著者 佐田 憲映|
発行日 2010-08-02
出版物タイトル 岡山医学会雑誌
122巻
2号
資料タイプ 学術雑誌論文
著者 佐田 憲映|
発行日 2006-12-31
出版物タイトル
資料タイプ 学位論文