著者 Yoshimura, Teizo| Howard, O. M. Zack| Ito, Toshihiro| Kuwabara, Masaki| Matsukawa, Akihiro| Chen, Keqiang| Liu, Ying| Liu, Mingyong| Oppenheim, Joost J.| Wang, Ji Ming|
発行日 2013-03-18
出版物タイトル PLOS ONE
8巻
3号
資料タイプ 学術雑誌論文
著者 Mazaki, Tetsuro| Shiozaki, Yasuyuki| Yamane, Kentaro| Yoshida, Aki| Nakamura, Mariko| Yoshida, Yasuhiro| Zhou, Di| Kitajima, Takashi| Tanaka, Masato| Ito, Yoshihiro| Ozaki, Toshifumi| Matsukawa, Akihiro|
発行日 2014-03-25
出版物タイトル Scientific Reports
4巻
資料タイプ 学術雑誌論文
著者 Shiozaki, Yasuyuki| Kitajima, Takashi| Mazaki, Tetsuro| Yoshida, Aki| Tanaka, Masato| Umezawa, Akihiro| Nakamura, Mariko| Yoshida, Yasuhiro| Ito, Yoshihiro| Ozaki, Toshifumi| Matsukawa, Akihiro|
発行日 2013-04
出版物タイトル International Journal of Nanomedicine
8巻
1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/51867
フルテキストURL 67_5_311.pdf
著者 Nishida, Keiichiro| Hashizume, Hiroyuki| Matsukawa, Akihiro| Hashizume, Kenzo| Shimamura, Yasunori| Torigoe, Yasuyuki| Ozaki, Toshifumi|
抄録 We report a case of 4th metacarpal head collapse of a 19-year-old healthy man. MRI revealed T1 low and T2 high regions in the collapsed 4th metacarpal head, as well as in the right 3rd and left 4th metacarpal head. Our initial diagnosis was occult compression fracture due to avascular necrosis, known as Dieterich's disease. However, pathological findings of surgically resected right 4th metacarpal head were compatible with transient osteoporosis and metacarpal head fracture followed by active tissue repair. The autologous osteochondral transplants from costchondral junction survived and maintained their size and shape even at 10-year follow-up.
キーワード occult compression fracture metacarpal head avascular necrosis osteochondral autograft
Amo Type Case Report
発行日 2013-10
出版物タイトル Acta Medica Okayama
67巻
5号
出版者 Okayama University Medical School
開始ページ 311
終了ページ 317
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24145731
Web of Sience KeyUT 000325836100005
著者 Wakabayashi, Hiroshi| Ito, Toshihiro| Fushimi, Soichiro| Nakashima, Yuki| Itakura, Jyunya| Liu, Qiuying| Win, Min Min| Sun, Cuiming| Chen, Cao| Sato, Miwa| Mino, Megumi| Ogino, Tetsuya| Makino, Hirofumi| Yoshimura, Akihiko| Matsukawa, Akihiro|
発行日 2012-09
出版物タイトル Clinical Immunology
144巻
3号
資料タイプ 学術雑誌論文
著者 八代 将登| 塚原 宏一| 松川 昭博| 山田 睦子| 藤井 洋輔| 長岡 義晴| 津下 充| 山下 信子| 伊藤 利洋| 山田 雅夫| 増谷 弘| 淀井 淳司| 森島 恒雄|
発行日 2013-08-01
出版物タイトル 岡山医学会雑誌
125巻
2号
資料タイプ 学術雑誌論文
著者 Yashiro, Masato| Tsukahara, Hirokazu| Matsukawa, Akihiro| Yamada, Mutsuko| Fujii, Yosuke| Nagaoka, Yoshiharu| Tsuge, Mitsuru| Yamashita, Nobuko| Ito, Toshihiro| Yamada, Masao| Masutani, Hiroshi|
発行日 2013-01
出版物タイトル Critical Care Medicine
41巻
1号
資料タイプ 学術雑誌論文
著者 樅木 勝巳| 高嶋 留美| 松川 昭博|
発行日 2011-05
出版物タイトル 岡山実験動物研究会報
27巻
資料タイプ 一般雑誌記事
JaLCDOI 10.18926/AMO/32897
フルテキストURL fulltext.pdf
著者 Matsukawa, Akihiro|
抄録 The innate immune system provides immediate defense against infection and serves as the first line of host defense during infection. In innate immunity, leukocytes such as neutrophils and macrophages recognize and respond to pathogens in a non-specific manner. Therefore, the recruitment and activation of leukocytes are essential in innate immunity, and are governed by a variety of chemical mediators including cytokines. Cytokines are generally divided into 2 types, termed type-1 and type-2 cytokines. Type-1 cytokines are important in local host defense, while type-2 cytokines play a protective role when inflammatory response spreads to the body. These cytokines exert their biological functions through the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. STAT1/3/4/6 are transcription factors that mediate IFNgamma/IL-10/IL-12/IL-13 cytokine signaling, respectively. Evidence indicates that STAT proteins have a significant impact on innate immunity during sepsis. This review focuses on recent understandings in the regulation of innate immunity by STAT proteins during sepsis and septic shock. The suppressor of cytokine signaling (SOCS) proteins are a family of SH2 domain-containing cytoplasmic proteins that complete a negative feedback loop to attenuate signal transduction from cytokines that act through the JAK/STAT pathway. The participation of SOCS proteins in sepsis is also discussed.
キーワード cytokines innate immunity sepsis SOCS STAT
Amo Type Review
発行日 2007-10
出版物タイトル Acta Medica Okayama
61巻
5号
出版者 Okayama University Medical School
開始ページ 239
終了ページ 245
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 17971840
Web of Sience KeyUT 000250431700001
著者 松川 昭博|
発行日 2006-09-01
出版物タイトル 岡山医学会雑誌
118巻
2号
資料タイプ 学術雑誌論文