フルテキストURL fulltext.pdf
著者 Baba, Yuki| Kawano, Seiji| Kono, Yoshiyasu| Inokuchi, Toshihiro| Kanzaki, Hiromitsu| Iwamuro, Masaya| Harada, Keita| Kawahara, Yoshiro| Okada, Hiroyuki|
キーワード obscure gastrointestinal bleeding overt previous bleeding vascular lesions chronic kidney disease
発行日 2020-06-01
出版物タイトル Internal Medicine
出版者 The Japanese Society of Internal Medicine
開始ページ 1345
終了ページ 1350
ISSN 1349-7235
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2020 by The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 32023585
DOI 10.2169/internalmedicine.3628-19
Web of Science KeyUT 000537806600001
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.3628-19
フルテキストURL fulltext.pdf
著者 Kinugasa, Hideaki| Hiraoka, Sakiko| Nouso, Kazuhiro| Yamamoto, Shumpei| Hirai, Mami| Terasawa, Hiroyuki| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Harada, Keita| Tanaka, Takehiro| Okada, Hiroyuki|
キーワード IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA
発行日 2020-12-03
出版物タイトル BMC Cancer
出版者 BMC
開始ページ 1188
ISSN 1471-2407
NCID AA12034763
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © The Author(s). 2020
論文のバージョン publisher
PubMed ID 33272240
DOI 10.1186/s12885-020-07699-z
Web of Science KeyUT 000597268700004
関連URL isVersionOf https://doi.org/10.1186/s12885-020-07699-z
JaLCDOI 10.18926/AMO/60363
フルテキストURL 74_4_265.pdf
著者 Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun|
抄録 Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy.
キーワード Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance
Amo Type Original Article
発行日 2020-08
出版物タイトル Acta Medica Okayama
出版者 Okayama University Medical School
開始ページ 265
終了ページ 274
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32843757
Web of Science KeyUT 000562508700001
NAID 120006880202
フルテキストURL fulltext.pdf
著者 Yasutomi, Eriko| Hiraoka, Sakiko| Yamamoto, Shumpei| Oka, Shohei| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Kato, Jun| Okada, Hiroyuki|
キーワード ulcerative colitis salicylates mesalazine sulfasalazine
発行日 2019-12-02
出版物タイトル Journal of Clinical Medicine
出版者 MDPI
ISSN 2077-0383
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2019 by the authors.
論文のバージョン publisher
PubMed ID 31810227
DOI 10.3390/jcm8122109
Web of Science KeyUT 000506640400082
関連URL isVersionOf https://doi.org/10.3390/jcm8122109
フルテキストURL SR9_1_11934.pdf
著者 Takahara, Masahiro| Takaki, Akinobu| Hiraoka, Sakiko| Adach, Takuya| Shimomura, Yasuyuki| Matsushita, Hiroshi| Nguyen Tien Thi Thuy| Koike, Kazuko| Ikeda, Airi| Takashima, Shiho| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Sugihara, Yusaku| Harada, Keita| Eikawa, Shingo| Morita, Hidetoshi| Udono, Heiichiro| Okada, Hiroyuki|
発行日 2019-8-15
出版物タイトル Scientific Reports
出版者 Nature Publishing Group
開始ページ 11934
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2019
論文のバージョン Publisher
PubMed ID 31417110
DOI 10.1038/s41598-019-48331-w
Web of Science KeyUT 000480680800048
関連URL isVersionOf https://doi.org/10.1038/s41598-019-48331-w
タイトル(別表記) Achalasia treated with per-oral endoscopic myotomy (POEM)
フルテキストURL 129_115.pdf
著者 杉原 雄策| 原田 馨太| 加藤 諒| 山内 健司| 高嶋 志保| 竹井 大介| 井口 俊博| 高原 政宏| 川野 誠司| 平岡 佐規子| 田辺 俊介| 野間 和宏| 白川 靖博| 眞部 紀明| 井上 晴洋| 岡田 裕之|
抄録 Esophageal achalasia is a disorder of the lower esophageal sphincter muscle. Patients present with dysphagia, chest pain, vomiting, and aspiration. Esophageal achalasia had traditionally been treated with esophageal achalasia balloon dilatation and the Heller-Dor method, but in recent years, the use of per-oral endoscopic myotomy (POEM) has increased. Our patient, a 39-yr-old male, began experiencing dysphagia 4 years prior to his referral to our hospital. Based on the results of esophagogastroduodenoscopy, esophageal radiography and high-resolution manometry, we made the diagnosis of esophageal achalasia (Chicago classification type I) . After informed consent from the patient and his family and approval from our hospital's ethics committee were obtained, we performed a POEM. The patient was discharged on the 4th day post-surgery. At the 1-year post-operative examination, no worsening of symptoms and no relapse were observed. POEM is an excellent treatment method for esophageal achalasia from the perspective of therapeutic effect and prevention of invasion. We recommend that it be considered as the first-choice treatment for achalasia. However, accessibility to the procedure itself is limited due to the few adequately trained operators worldwide. POEM should thus be performed by an expert operator at a high-volume center.
キーワード POEM 食道アカラシア (esophageal achalasia)
出版物タイトル 岡山医学会雑誌
発行日 2017-08-01
開始ページ 115
終了ページ 121
ISSN 0030-1558
関連URL https://doi.org/10.4044/joma.129.115
言語 Japanese
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.115
NAID 130006039377
タイトル(別表記) Adenocarcinoma in the jejunum 20 years after surgery for familial adenomatous polyposis
フルテキストURL 129_111.pdf
著者 杉原 雄策| 川野 誠司| 原田 馨太| 高嶋 志保| 竹井 大介| 井口 俊博| 高原 政宏| 平岡 佐規子| 母里 淑子| 岸本 浩行| 永坂 岳司| 岡田 裕之|
抄録 A 58-year-old Japanese man visited a local clinic for the evaluation of a stomachache. He was diagnosed with intestinal obstruction. His medical history included a proctocolectomy at the age of 38 years, due to familial adenomatous polyposis (FAP). He was referred to our institution, where he underwent a computed tomography examination and endoscopy of the small intestine. The pathological diagnosis was adenocarcinoma. No invasive or metastatic lesions were observed. Therefore, partial resection of the ileum with lymphadenectomy and reconstruction of the ileostomy were performed. Pathological examination revealed that the tumor was type 2, pT3 (SS) , pN1, pPM0, pDM0, pRM0, INFb, ly1, v1, pEX0, PN0. Twenty-nine days after the surgery, the patient was diagnosed with lung metastasis and he underwent lung radiofrequency ablation. We suggest that long-term follow-up is necessary for patients after surgery for FAP, because of the risk of malignant disease developing in other organs.
キーワード 家族性大腸腺腫症 (familial adenomatous polyposis) 小腸癌 (jejunal cancer) 小腸内視鏡検査 (small intestine endoscope)
出版物タイトル 岡山医学会雑誌
発行日 2017-08-01
開始ページ 111
終了ページ 114
ISSN 0030-1558
関連URL https://doi.org/10.4044/joma.129.111
言語 Japanese
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.111
NAID 130006039373
著者 岩室 雅也| 岡田 裕之| 原田 馨太| 神崎 洋光| 堀 圭介| 喜多 雅英| 川野 誠司| 河原 祥朗| 田中 健大| 山本 和秀|
発行日 2016-12-01
出版物タイトル 岡山医学会雑誌
資料タイプ 学術雑誌論文
著者 半井 明日香| 加藤 順| 平岡 佐規子| 栗山 宗彰| 井口 俊博| 竹井 大介| 森藤 由記| 秋田 光洋| 高橋 索真| 原田 馨太| 岡田 裕之| 山本 和秀|
発行日 2013-12-02
出版物タイトル 岡山医学会雑誌
資料タイプ 学術雑誌論文